Key PublicationsDiagnosisTreatmentScreeningCost-effectiveness of Screening
- Boulware, D.,R, Meya, D., Muzoora, C. et al.(2014) Timing of Antiretroviral Therapy after Diagnosis of Cryptococcal Meningitis
- Ganiem A.R., Indrati A.R., Wisaksana R., Meijerink H., Andre van der Ven., Alisjahbana,B., et al. (2014) Asymptomatic cryptococcal antigenemia is associated with mortality among HIV-positive patients in Indonesia
- Ahmad Rizal Ganiem, Agnes Rengga Indrati, Rudi Wisaksana, Hinta Meijerink, Andre van der Ven, Bachti Alisjahbana, Reinout van CrevelAhmad Rizal Ganiem, Agnes Rengga Indrati, Rudi Wisaksana, Hinta Meijerink, Andre van der Ven, Bachti Alisjahbana, Reinout van CrevelChim B., Piseth S., S., Heng V., H., Sopheak T., et al. (2013). Integrated Cryptococcal Antigen Screening and Pre-Emptive Treatment Prior to Initiation of Antiretroviral Treatment in Cambodia
- Beyene et al. (2013) Comparison of Cryptococcal Antigenemia between Antiretroviral Naïve and Antiretroviral Experienced HIV Positive Patients at Two Hospitals in Ethiopia
- Javis N. J., Harrison S.T., Lawn S.D., et al. ( 2013). Cost Effectiveness of Cryptococcal Antigen Screening as a Strategy to Prevent HIV-Associated Cryptococcal Meningitis in South Africa
- Perfect J.R., (2013). Efficiently Killing a Sugar-Coated Yeast (Please scroll down to the bottom of the first page to read the article)
- Smith R.M., Nguyen T. A., et al (2013). Prevalence of Cryptococcal Antigenemia and Cost-Effectiveness of a Cryptococcal Antigen Screening Program – Vietnam
- Yansouri C.P., Bottieau E., Lutumba P. et al (2013). Rapid diagnostic tests for neurological infections in central Africa
- Hansen J., Slechta S., Gates-Hollingworth M. A., et al. (2013). Large-Scale Evaluation of the Immuno-Mycologics Lateral Flow and Enzyme-Linked Immunoassays for Detection of Cryptococcal Antigen in Serum and Cerebrospinal Fluid
- Day J. N., Chau T. T., Wolbers M., et al. (2013). Combination Antifungal Therapy for Cryptococcal Meningitis
- Alemu A. S., Kempker R. R.,et al. (2013) High Prevalence of Cryptococcal Antigenemia among HIV-infected Patients Receiving Antiretroviral Therapy in Ethiopia
- Gates-Hollingsworth., M. A., Kozel. T.,R. (2013). Serotype Sensitivity of a Lateral Flow Immunoassay for Cryptococcal Antigen
- Andama. A., O., S. den Boon. S. et al (2013). Prevalence and Outcomes of Cryptococcal Antigenemia in HIV-seropositive Patients Hospitalized for Suspected Tuberculosis in Uganda
- Meyer A. -C., Kendi. C., K. et al (April 2013) The impact of routine cryptococcal antigen screening on survival among HIV-infected individuals with advanced immunosuppression in Kenya
- Alemu A., S., Kempker. R., R., Tenna. A., et al. (March 2013), High Prevalence of cryptococcal Antigenemia among HIV-infected Patients Receiving Antiretroviral Therapy in Ethiopia
- Vijayan T., Klausner. D., et al. (March 2013) Sensitivity and specificity of a new cryptococcal antigen lateral flow assay in serum and cerebrospinal fluid
- Binnicker M.J, Jespersen D. J., Bestrom J.E., Rollins L.O. Comparison of four assays for the detection of cryptococcal antigen. Clin Vaccine Immunol. 2012;19(12):1988-1990.
- McMullan BJ, Halliday C, Sorrell TC, et al. Clinical Utility of the Cryptococcal Antigen Lateral Flow Assay in a Diagnostic Mycology Laboratory. PLoS One. 2012; 7(11): e49541.
- Govender, N. P et al. Phased implementation of screening for cryptococcal disease in South Africa (2012)
- Reconsidering Cryptococcal Antigen Screening in the U.S. among persons with CD4<100 cells/mcL
- Park, B.J. et al. Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS. AIDS (2009) 23:525. PUBMED Link Only
- Roy, M. et al. Preventing deaths from cryptococcal meningitis: from bench to bedside. Expert Rev. Anti Infect. Ther. (2011) 9:715.
- Meya, D.B. et al. Cost-effectiveness of serum cryptococcal antigen screening to prevent deaths among HIV-infected persons with a CD4+ cell count ≤100 cells/μl who start HIV therapy in resource-limited settings. Clin. Infect. Dis. (2010) 51:448.
- Rajasingham, R. et al. Integrating cryptococcal antigen screening and pre-emptive treatment into routine HIV care. J Acquir Immune Defic Syndr. (2012) 59:5.
- Rutherford, G. et al. The performance of serum cryptococcal antigen (CrAg) latex agglutination testing for diagnosis of cryptococcal meningitis (CM): a systematic review. AIDS 2012 WEPE026
- CROI 2012 Cryptococcal Meningitis: Advances in Diagnosis and Management Webcast
- Rolfes, M. et al. Evaluation of a novel point-of-care lateral flow assay to detect cryptococcal antigen in plasma and CSF. CROI 2012 Abstract 953
- Harris, J.R.et al. High prevalence of cryptococcal infection among HIV-infected patients hospitalized with pneumonia in Thailand. Clin. Infect. Dis. (2012) 54:e43. PUBMED Link Only
- Vanselow, M. et al. Diagnosis and management of cryptococcal disease in resource-limited settings. Curr. Fungal Infect. Rep. (2012) 6:35 PUBMED Link Only
- Lindsley, M.D. et al. Evaluation of a newly developed lateral flow immunoassay for the diagnosis of cryptococcosis. Clin. Infect. Dis. (2011) 53:321.
- Jarvis, J.N. et al. Evaluation of a novel point-of-care cryptococcal antigen test on serum, plasma, and urine from patients with HIV-associated cryptococcal meningitis. Clin. Infect. Dis. (2011) 53:1019. PUBMED Link Only
- Cachay, E.R. et al. Utility of clinical assessment, imaging, and cryptococcal antigen titer to predict AIDS-related complicated forms of cryptococcal meningitis. AIDS Res. Ther. (2010) 7:29.
- Saha, D.C. et al. Evaluation of conventional & serological methods for rapid diagnosis of cryptococcosis. Indian J Med Res 127, May 2008, pp 483-488
- Antinori, S. et al. The role of cryptococcal antigen assay in diagnosis and monitoring of cryptococcal meningitis. J Clin Microbiol. 2005 Nov;43(11):5828-9.
- Powderly, W.G. et al. Measurement of cryptococcal antigen in serum and cerebrospinal fluid: value in the management of AIDS-associated cryptococcal meningitis. Clin. Infect. Dis. (1994) 18:789. PUBMED Link Only
- Tanner, DC. et al. Comparison of commercial kits for detection of cryptococcal antigen. J Clin Microbiol. 1994 Jul;32(7):1680-4.
- Swinne, D. et al. Evaluation of the cryptococcal antigen test as a diagnostic tool of AIDS-associated cryptococcosis in Rwanda. Ann Soc Belg Med Trop. 1992 Dec;72(4):283-8.
- Jackson, A. and van der Horst, C. New Insights in the Prevention, Diagnosis, and Treatment of Cryptococcal Meningitis. DOI: 10.1007/s11904-012-0127-7
- Makadzange, A. et al. Early versus Delayed Initiation of Antiretroviral Therapy for Concurrent HIV Infection and Cryptococcal Meningitis in Sub-Saharan Africa. Clin Infect Dis. (2010) 50 (11): 1532-1538. doi: 10.1086/652652
- Zolopa AR, Andersen J, Komarow L, Sanne I, Sanchez A, et al. (2009) Early Antiretroviral Therapy Reduces AIDS Progression/Death in Individuals with Acute Opportunistic Infections: A Multicenter Randomized Strategy Trial. PLoS ONE 4(5): e5575. doi:10.1371/journal.pone.0005575
- Jackson, A. et al. Management of cryptococcal meningitis in sub-saharan Africa. Curr HIV/AIDS Rep. 2010 Aug;7(3):134-42.
- Sloan, D. et al. Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings. Cochrane Database Syst Rev. 2008 Oct 8;(4):CD005647.
- Meya, D. et al. Cost benefit of integrating cryptococcal antigen screening and preemptive treatment into routine HIV care. AIDS 2012 MOAB0102
- Jarvis, J.N. et al. Cost effectiveness of cryptococcal antigen screening as a strategy to prevent HIV-associated cryptococcal meningitis in South Africa. Intl. AIDS Society 2011 Abstract WELBD02.
- Micol, R. et al. Cost-effectiveness of primary prophylaxis of AIDS associated cryptococcosis in Cambodia. PLoS ONE (2010) 5:e13856.
- Meya, D.B. et al. Cost-effectiveness of serum cryptococcal antigen screening to prevent deaths among HIV-infected persons with a CD4+ cell count ≤100 cells/μl who start HIV therapy in resource-limited settings. Clin. Infect. Dis. (2010) 51:448.
- Pongsai, P. et al. The role of serum cryptococcal antigen screening for the early diagnosis of cryptococcosis in HIV-infected patients with different ranges of CD4 cell counts. J. Infect. (2010) 60:474. PUBMED Link Only
